flywire

A curated list of fruit fly connectome projects: MaleCNS, FlyWire, brain simulations, embodied models, games, and research tools.

Explore the FlyWire Connectome

Python library for analysis of neuroanatomical data.

Embodied Drosophila: 138,639-neuron whole-brain connectome simulation (FlyWire v783) in a biomechanical body (NeuroMechFly v2 / MuJoCo). Vision, olfaction, gustation, flight, and emergent behaviors — all from the real connectome.

Tools to work with the FlyWire connectome. Fully interoperable with navis.

🪰 Chat with 138,000 neurons — whole-brain fruit fly simulation with natural language interface and dopamine learning

把果蝇全脑连接组跑在一台 16GB 笔记本上：接身体、做成浏览器游戏、17,628 次虚拟敲除。完整记录能做什么、做不到什么，以及自查出的每一处错误。Code GPL-3.0+, data CC BY-NC.

Windows port (C#/.NET 8/Direct3D11) of desktop-vibe-fly - a 3D fruit fly on your desktop driven by a live FlyWire connectome simulation, with a vibecode nose for AI agent activity. Fork/port of kulikov0/desktop-vibe-fly, itself a fork of DenisSergeevitch/desktop-fly.

Linux/X11 port of DesktopFly (desktop-fly): a 3D fruit fly on your GNOME desktop, driven by a live spiking simulation of the real FlyWire connectome. Python + GTK3 + cairo, no Electron.

Stimulate a real fruit fly's brain in your browser. Leaky integrate-and-fire over the FlyWire connectome — 138,639 neurons, 2.7M connections, 60 fps, no dependencies.

Virtual organisms powered by real brain wiring. Connectome data → spiking neural network → physics body → emergent behavior.

Poke a neuron in the fruit fly brain and watch what fires: a laptop-speed LIF simulation of the full FlyWire connectome

A living fruit fly in your browser. Feed it and its real feeding circuit fires — 448 neurons from the Drosophila connectome, simulated live.

FlyWire FAFB v783 connectome as a ready-to-train PyTorch Geometric dataset: 139,255 neurons, 2.7M edges, 9-class node classification, real CPU baselines (MLP 0.9851 / SAGE 0.9812 / GCN 0.9166)

Real audio in, real neurons firing, real time. No samples, no playback tricks: it listens to whatever your PC is currently playing.

把 FlyWire 完整果蝇脑连接组（139,255 个神经元 / 269 万条突触连接）跑在鸿蒙手机上 —— ArkTS + ArkGraphics 3D 原生 App，端侧 LIF 神经仿真实时放电并驱动果蝇行为。

Behavioural benchmark for whole-brain fruit fly connectome simulations: 31 pre-registered, cited tasks on FlyWire v783 and MaleCNS, shuffled-wiring controls, a reference LIF and the first cross-model comparison (spike-frequency adaptation beats it).

Fruit fly connectome lab: real FlyWire pursuit circuit (3,963 neurons, no training) aims a gun on the web and plays Doom, with scrambled-wiring and lesion controls

Sparse, model-agnostic harness for deployed biological simulations.

60 FPS engine-free 3D pond in ~2.3k lines of Python: 9 fly agents, one driven by LIF spiking circuits (GF/CX/REST) — plus the real NeuroMechFly model (126 DoF, 721 ommatidia/eye) assembled and rendered on MuJoCo.